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Regenerating Skin longevity

Step 4: Moisturize

Night Cream Intense

Sale price$79.90 USDIn stock

Tax excluded.

5-ALA & Resveratrol - support skin renewal and provide powerful antioxidant protection

Shea Butter & Squalane - deeply nourish the skin and help prevent moisture loss

Japanese Botanicals - protect against environmental stressors and help prevent premature skin aging

Loved by our customers

Skin looks visibly smoother and more restored upon waking.

Who is this product ideal for?

Perfect for anyone wanting to deeply nourish their skin overnight and counteract signs of fatigue - ideal for mature or dry skin.

Description

Regenerating Night Care with 5-ALA and resveratrol – For maximal rested, smooth skin


Our KIYOMI SKIN Night Cream Intense from the TATEYAMA Series provides your skin with everything it needs for a deep, overnight regeneration. With its innovative formula combining 5-ALA and resveratrol, tired, stressed skin is revitalized overnight and its natural radiance is restored.

Your skin will love resveratrol


Resveratrol, a powerful antioxidant known for its anti-aging properties, protects the skin from free radicals and environmental damage that can lead to premature skin aging. It supports the natural skin barrier and promotes regeneration while you sleep.

Why your skin will benefit from this Night Cream:


  • Deep regeneration: 5-ALA supports skin renewal, strengthens the skin barrier, and promotes a firmer, smoother complexion.
  • Slows down skin aging: 5-ALA, vitamin E, and turmeric root extract boost elasticity and combat visible signs of aging.
  • Protection with resveratrol: This antioxidant protects the skin from harmful environmental factors and enhances its natural resilience.
  • Moisture boost: Squalane and shea butter provide deep moisture and leave the skin feeling silky smooth.
  • Soothing & balancing: Extracts from traditional Japanese herbs such as angelica root and shikon soothe the skin and promote a relaxed skin feeling.

Refreshed skin by morning


Our Night Cream Intense offers your skin the perfect combination of moisture, protection, and regeneration – for radiant, smooth, and strengthened skin every morning.
Application

Use the Night Cream Intense every evening after cleansing and, if desired, after applying a serum. Apply a pea-sized amount to your face and gently massage in circular motions until the cream is fully absorbed.

Ingredients

Water, Squalane, Glycerin, Pentylene Glycol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Microcrystalline Cellulose, Butyrospermum Parkii (Shea) Butter, Cetyl Alcohol, 1,2-Heptanediol, Stearyl Alcohol, Aminolevulinic Acid Phosphate, Pichia/Resveratrol Ferment Extract, Resveratrol, Diammonium Ferric Pentetate, Xanthan Gum, Butylene Glycol, Hydroxypropyl Starch Phosphate, Citric Acid, Leuconostoc/Radish Root Ferment Filtrate, Sodium Citrate, Lavandula Angustifolia (Lavender) Oil, Angelica Acutiloba Root Extract, Curcuma Longa (Turmeriv) Extract, Lithospermum Officinale Root Extract, Phellodendron Amurense Bark Extract, Phytic Acid, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Ascorbyl Isostearate, Arginine, Ascorbic Acid

Füllmenge: 1,6 fl.oz. / 50ml

Sale price$79.90 USD

Packaged in Italian Glass

No Parabens or Silicones

Cruelty-free

No Perfume

GMO-free

No Microplastics

Where Science Meets Results

How 5-ALA Helps Your Skin Reveal Its Best Self

1. Activate Cellular Energy
As we age, our cells produce less energy - the skin can appear dull, tired, and less radiant. 5-ALA helps re-energize these natural processes, giving your skin newfound vitality and a visibly brighter look.

2. Support Skin Regeneration

With renewed energy, your skin can better support its natural repair and renewal cycles. Your complexion appears more refreshed, balanced, and restored.

3. Strengthen Skin Structure
5-ALA supports the formation of collagen and elastin, helping your skin maintain firmness - the foundation of smooth, supple skin texture.

4. Preserve Skin Hydration
Over time, the skin barrier becomes more delicate. By supporting healthy cellular metabolism, 5-ALA helps strengthen the barrier so your skin can retain moisture more effectively. The result: a nourished, protected, comfortably hydrated skin feel.

The Results Our Community Loves

Preventive Skincare

Looking for skincare that works early and supports your skin in the long run?

We believe in preventive skincare powered by 5-ALA.

5-ALA supports cellular activity and keeps your skin’s natural renewal processes moving - for smoother, clearer-looking skin today and the confidence of knowing your complexion will stay radiant tomorrow.

Deep Hydration

Dry, tight skin even though you’re using rich moisturizers?

Moisture alone isn’t always enough - your skin needs support to hold on to it. Clinical studies show that 5-ALA sustainably improves the skin’s moisture levels.

The result: skin that looks plump, fresh, and deeply hydrated.

Natural Glow Booster

Dull, tired-looking skin - even with a dedicated routine?

In many cases, the skin is simply lacking energy. Our active ingredient 5-ALA supports mitochondrial processes essential for cellular energy production - helping your skin regain its radiance quickly and naturally.

Refined Skin Texture

Uneven texture or enlarged pores?

This is often linked to a slowed cellular renewal process.

5-ALA supports the natural renewal cycle and helps rebalance overall skin texture - for visibly refined pores, smoother contours, and a more even-looking complexion.

Skin in Balance

Does your skin tend to flush easily or look stressed?

A slowed-down renewal process is often the reason.

Our active ingredient 5-ALA supports natural regeneration and reinforces the skin’s protective functions. As a result, redness fades, irritation calms, and your complexion looks noticeably more even.

Ingredients

These Ingredients Make the Difference

Resveratrol

A powerful plant-derived antioxidant from Japanese knotweed. Protects the skin from environmental stressors, helps prevent premature aging, and supports natural renewal.

Ideal for: protection, renewal, radiance

Shea Butter

Extracted from the nuts of the African shea tree, rich in vitamins and essential fatty acids. Deeply nourishes, protects against moisture loss, and leaves the skin soft and supple.

Ideal for: nourishing care, protection, softness

Japanese Herbal Extracts

A blend of traditional Japanese plant extracts such as angelica, turmeric, lithospermum, and phellodendron. They provide antioxidant benefits, soothe the skin, and support regeneration.

Ideal for: soothing, protection, regeneration

Step 1 -
Apply

In the evening, apply a pea-sized amount to clean skin. For more targeted benefits, layer a suitable serum underneath.

Step 2 -
Work In

Gently massage it in with your fingertips using soft, circular motions.

Step 3 -
Let It Absorb

Let it sink in overnight and enjoy its restorative, replenishing benefits while you sleep.

FAQs

More questions? We're here to help!

Contact Us

What is 5-ALA in skincare?

5-ALA (5-Aminolevulinic Acid) is a naturally occurring amino acid that supports cellular energy production.

Found in small amounts in foods like spinach and tomatoes, 5-ALA helps energize skin cells, making it a powerful ingredient for improving hydration, firmness, and glow.

How does 5-ALA work on the skin?

5-ALA stimulates the mitochondria, known as the "powerhouses" of cells.

This boosts the production of ATP (cellular energy), which helps the skin to generate collagen and elastin, retain moisture, and regenerate more effectively - resulting in smoother, more radiant skin.

Is 5-ALA safe for daily use?

All our 5-ALA skincare products are dermatologically tested and suitable for daily use as part of your skincare routine.

When can I expect to see visible results with 5-ALA skincare?

In a clinical study, participants saw a measurable increase in skin hydration after just 4 weeks, along with a visible reduction in wrinkle depth and fine lines. Results may vary depending on skin type and consistency of use.

Is 5-ALA a natural skincare ingredient?

Yes. 5-ALA occurs naturally in the human body and in small amounts in foods like spinach, tomatoes, and potatoes.

In skincare, it is biotechnologically derived for purity, safety, and effectiveness.

Can I combine 5-ALA with other skincare ingredients?

Absolutely. 5-ALA pairs well with hydrating agents like hyaluronic acid, barrier-supporting ingredients like ceramides, and even brightening actives like Vitamin C. It’s a versatile and gentle base for many routines.

Is there scientific research supporting the effectiveness of 5-ALA in skincare?

Yes. A Japanese double-blind clinical study confirmed that 5-ALA significantly increased skin moisture and reduced the depth of wrinkles after just four weeks of regular use.

Source: Naraoka et al., Health Journal, 2020.

Is 5-ALA vegan and cruelty-free?

Yes. The 5-ALA used in KIYOMI SKIN products is vegan, biotechnologically produced, and our skincare is never tested on animals.

What are the skincare benefits of 5-ALA?

5-ALA is ideal for anyone looking to:

  • Deep hydration and moisture retention
  • Visible reduction in fine lines and wrinkles
  • Improved skin elasticity and firmness
  • Supports cell renewal and repair
  • Long-term radiance and skin resilience

Is 5-ALA safe for all skin types?

Yes. 5-ALA is dermatologically tested and considered safe for all skin types, including sensitive skin.

At KIYOMI SKIN, we formulate with clean, biocompatible ingredients to ensure high tolerance and daily use.

Who should use 5-ALA skincare products?

5-ALA is perfect for those looking to:

  • Improve skin hydration and glow
  • Prevent or reduce signs of aging
  • Boost collagen production naturally
  • Strengthen and support skin from the inside out
  • Build a science-based, minimalist skincare routine.
Your Feedback

Kiyomi Community

@elizabethakelsey

Since I’m now 42, taking care of my skin is a priority for me. I love using natural products, fragrance-free products and I’m currently trying out the intensive night cream, which is super hydrating!

@mrsclairemclain

It’s this glow boost that truly makes the difference for me

@french_rustic_designs

My face has been very dry and it has really helped reduce dry patches and leaves my skin looking more radiant in the morning. I also like that a little goes a long way, so the jar will last quite a while.

Reviews