Step 2: Serum
5-ALA Radiance Booster Serum
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Loved by our customers
Who is this product ideal for?
Whether you're noticing dehydration, uneven tone or the first signs of aging, this daily serum helps support stronger, smoother and more radiant-looking skin.
Description
Meet 5-ALA: Where Skin Energy Begins
Most serums focus on the visible signs of skin aging - fine lines, dullness and dehydration. The 5-ALA Radiance Booster Serum takes a different approach by supporting the skin's natural energy processes for healthier-looking, more radiant skin. Rather than simply masking visible signs of fatigue, it helps promote skin that looks refreshed, hydrated and resilient.
Meet Kiyomi Skin's most advanced formula yet
At the heart of the formula is our highest-ever concentration of 5-ALA Phosphate(5-aminolevulinic acid), a naturally occurring molecule involved in the body's mitochondrial energy pathway. We paired our signature ingredient with exosome-inspired plant-derived vesicle technology, designed to help optimize ingredient delivery, alongside rare Japanese Suizenji-nori, prized for centuries for its exceptional ability to help maintain lasting hydration and support the skin's natural moisture barrier.
What Is 5-ALA, and Why Does Skin Energy Decline After 30?
If you've never heard of Kiyomi Skin or 5-ALA before, you're not alone - most people in the US haven't, yet.
In Japan, 5-Aminolevulinic Acid Phosphate (5-ALA) has been studied and used in dermatology for decades. It's the amino acid your own cells already use to fuel their energy production - the same energy skin depends on to renew, repair, and glow.
Research suggests the body's natural 5-ALA production begins to decline as early as your 30s, at the same time skin's own renewal slows down. Less cellular energy means slower repair, a weaker barrier, and the dullness, dehydration, and fine lines that follow.
The 5-ALA Radiance Booster Serum is Kiyomi Skin's most concentrated expression of that science yet, built to work with skin, not against it.
Independently Tested. Real Results in 28 Days.
The 5-ALA Radiance Booster Serum was independently tested by an accredited European cosmetic testing laboratory, in a 28-day instrumental study with dermatological supervision. After four weeks of twice-daily use:
- Skin hydration increased by an average of +21%
- Skin barrier function improved, with a 34% average reduction in transepidermal water loss
- Skin elasticity and firmness increased by an average of +17%
- Skin smoothness improved by an average of +20%
The formula also earned a Dermatest "Excellent" rating and was well tolerated across all skin types, including sensitive skin.
Independent, peer-reviewed research on 5-ALA (Naraoka et al., Health, 2020) supports this: in a double-blind study of 45 women, 5-ALA phosphate-containing cosmetics significantly increased skin moisture and reduced the visible depth of wrinkles over eight weeks.
Five Ways 5-ALA Supports Your Skin
Barrier & Hydration
5-ALA, Panthenol, Tremella Fuciformis, and Saccharomyces Ferment Filtrate work together to strengthen the skin barrier and lock in moisture.
Smoothing & Renewal
5-ALA, Adenosine, Niacinamide, Acmella Oleracea, and Centella Asiatica support skin's natural renewal process, for a visibly smoother, more refined texture.
Brightening & Tone-Evening
5-ALA, Niacinamide, Rice Ferment, Saccharomyces Ferment Filtrate, and Phytic Acid help even out tone and restore radiance to a dull complexion.
Soothing & Calming
Panthenol, Centella Asiatica, Acmella Oleracea, and Saccharomyces Ferment Filtrate calm the look of redness and sensitivity.
Antioxidant Defense
Vitamin E, Lotus Root, Rice Ferment, Phytic Acid, and Saccharomyces Ferment Filtrate help protect skin against everyday environmental stress.
Rooted in Japanese Skincare Philosophy
Kiyomi Skin's approach is grounded in the Japanese philosophy of KI (energy), KIYOI (purity), and MI (beauty) — the belief that lasting radiance comes not from fighting the skin, but from supporting the energy it already has. We call this well-aging, not anti-aging: skin that is cared for, not corrected. The 5-ALA Radiance Booster Serum is Kiyomi Skin's most concentrated expression of that philosophy yet.
Sources: Independent instrumental and consumer-use studies conducted by Chemicos Group Sp. z o.o. (2026) under dermatological supervision; Naraoka et al., "Effect of 5-Aminolevulinic Acid-containing Supplement and Skin Care Formula on Skin Conditions," Health, 2020.
Size: 1 fl.oz. / 30ml
Packaged in Italian Glass
No Parabens or Silicones
Cruelty-free
No Perfume
GMO-free
No Microplastics
The Results Our Community Loves
Deep Hydration
Natural Glow Booster
Skin in Balance
Preventive Skincare
Refined Skin Texture
These Ingredients Make the Difference
Centella Asiatica Leaf Vesicles
Suizenji-nori (Aphanothece sacrum) Extract
Snow Mushroom Extract
Step 1 -
Apply
Step 2 -
Work In
Step 3 -
Lock In
5-ALA (5-Aminolevulinic Acid) is a naturally occurring amino acid that supports cellular energy production.
Found in small amounts in foods like spinach and tomatoes, 5-ALA helps energize skin cells, making it a powerful ingredient for improving hydration, firmness, and glow.
5-ALA stimulates the mitochondria, known as the "powerhouses" of cells.
This boosts the production of ATP (cellular energy), which helps the skin to generate collagen and elastin, retain moisture, and regenerate more effectively - resulting in smoother, more radiant skin.
All our 5-ALA skincare products are dermatologically tested and suitable for daily use as part of your skincare routine.
In a clinical study, participants saw a measurable increase in skin hydration after just 4 weeks, along with a visible reduction in wrinkle depth and fine lines. Results may vary depending on skin type and consistency of use.
Yes. 5-ALA occurs naturally in the human body and in small amounts in foods like spinach, tomatoes, and potatoes.
In skincare, it is biotechnologically derived for purity, safety, and effectiveness.
Absolutely. 5-ALA pairs well with hydrating agents like hyaluronic acid, barrier-supporting ingredients like ceramides, and even brightening actives like Vitamin C. It’s a versatile and gentle base for many routines.
Yes. A Japanese double-blind clinical study confirmed that 5-ALA significantly increased skin moisture and reduced the depth of wrinkles after just four weeks of regular use.
Source: Naraoka et al., Health Journal, 2020.
Yes. The 5-ALA used in KIYOMI SKIN products is vegan, biotechnologically produced, and our skincare is never tested on animals.
5-ALA is ideal for anyone looking to:
- Deep hydration and moisture retention
- Visible reduction in fine lines and wrinkles
- Improved skin elasticity and firmness
- Supports cell renewal and repair
- Long-term radiance and skin resilience
Yes. 5-ALA is dermatologically tested and considered safe for all skin types, including sensitive skin.
At KIYOMI SKIN, we formulate with clean, biocompatible ingredients to ensure high tolerance and daily use.
5-ALA is perfect for those looking to:
- Improve skin hydration and glow
- Prevent or reduce signs of aging
- Boost collagen production naturally
- Strengthen and support skin from the inside out
- Build a science-based, minimalist skincare routine.
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