Slow-aging Revitalizing

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Step 4: Moisturize

Night & Day Intense Duo

Name: Night & Day Intense Duo
Brand: Kiyomi Skin US
SKU: 15061-US
Price: 129.90 USD
Availability: InStock

$129.90 USD

$159.80 USD

In stock

Tax excluded.

Intense Daily Hydration - deeply moisturizes and improves elasticity for smoother, fresher-looking skin all day.

Overnight Repair & Firming - supports barrier strength and collagen renewal to wake up with firmer, renewed skin.

24/7 Age-Defying Care - targets dryness, fine lines, and dullness—revealing a more supple, radiant complexion.

Loved by our customers

Loved for its rich hydration and powerful regeneration, this duo keeps skin visibly smoother, plumper, and more radiant

Who is this product ideal for?

Ideal if your skin craves deep hydration, renewed firmness, and rich overnight repair - perfect for dry or mature skin.

Description

Perfect All-Around Care: Intensive Day and Night Cream for Radiance and Regeneration

Looking for a reliable skincare that deeply hydrates and protects your skin? The Night & Day Intense Duo combines an intensive day cream and a regenerating night cream, specifically designed to meet your skin’s natural needs—for a radiant, visibly smoother complexion.

Day Cream with Double Amount of 5-ALA and Japanese Herbs for Smooth, Radiant Skin

Our Day Cream Intense offers:

Double the 5-ALA Amount*: The natural amino acid 5-ALA provides intense hydration and protection.
Deep Hydration: Enhanced by 5-ALA and plant-based ingredients like squalane.
Anti-Aging Effect: Visibly reduces early signs of aging and improves the skin density.**
Collagen Boost: Thanks to vitamin E, which promotes the collagen synthesis.
Revitalizing Benefits: With antioxidant Japanese herbal extracts inspired by traditional medicine.

Night Cream with 5-ALA and Resveratrol for Intensive Regeneration and Recovery

Our Night Cream Intense offers:

Regenerative Nighttime Care: Combines 5-ALA and resveratrol to restore your skin’s natural glow.
Deep Moisturization: Provides intense hydration and combats signs of fatigue.
Soothing Care: Infused with shea butter and calming extracts for gentle nourishment and relaxed skin.
Environmental Defense: Resveratrol protects against free radicals and environmental damage.
Overnight Recovery: Supports skin repair while you sleep, leaving it refreshed and revitalized by morning.

The Night & Day Intense Duo is free from parabens, sulfates, and artificial fragrances, making it suitable for all skin types, including sensitive skin.

Give Your Skin the Care It Deserves

Achieve a radiant complexion during the day and rejuvenated, well-rested skin by morning.

*Double the amount of 5-ALA compared to KIYOMI SKIN Face Cream.

**Measured results from an external, independent instrumental application study, efficacy tests conducted July/August 2023, with 20 participants over 28 days of daily use.

Application

Daily apply a pea-sized amount of Day Cream Intense (in the morning) or Night Cream Intense (in the evening) to your cleansed face. Gently massage in circular motions and allow it to fully absorb.

Ingredients

Daycream Intense:
Water, Squalane, Propylene Glycol, Pentylene Glycol, Glycerin, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Microcrystalline Cellulose, Butyrospermum Parkii (Shea) Butter, Cetyl Alcohol, Xanthan Gum, Stearyl Alcohol, Lactic Acid, Aminolevulinic Acid Phosphate, Diammonium Ferric Pentetate, Butylene Glycol, Hydroxypropyl Starch Phosphate, Citric Acid, Sodium Citrate, Tocopherol, Lavandula Angustifolia (Lavender) Oil, Angelica Acutiloba Root Extract, Curcuma Longa (Turmeric) Rhizome Extract, Lithospermum Officinale Root Extract, Phellodendron Amurense Bark Extract, Arginine, Phytic Acid, Silver Citrate

Nighcream Intense:
Water, Squalane, Glycerin, Pentylene Glycol, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Cetearyl Glucoside, Glyceryl Stearate, Microcrystalline Cellulose, Butyrospermum Parkii (Shea) Butter, Cetyl Alcohol, 1,2-Heptanediol, Stearyl Alcohol, Aminolevulinic Acid Phosphate, Pichia/Resveratrol Ferment Extract, Resveratrol, Diammonium Ferric Pentetate, Xanthan Gum, Butylene Glycol, Hydroxypropyl Starch Phosphate, Citric Acid, Leuconostoc/Radish Root Ferment Filtrate, Sodium Citrate, Lavandula Angustifolia (Lavender) Oil, Angelica Acutiloba Root Extract, Curcuma Longa (Turmeriv) Extract, Lithospermum Officinale Root Extract, Phellodendron Amurense Bark Extract, Phytic Acid, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Ascorbyl Isostearate, Arginine, Ascorbic Acid

Füllmenge: Kit

$129.90 USD

$159.80 USD

Packaged in Italian Glass

No Parabens or Silicones

Cruelty-free

No Perfume

GMO-free

No Microplastics

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Where Science Meets Results

How 5-ALA Helps Your Skin Reveal Its Best Self

1. Activate Cellular Energy
As we age, our cells produce less energy - the skin can appear dull, tired, and less radiant. 5-ALA helps re-energize these natural processes, giving your skin newfound vitality and a visibly brighter look.

2. Support Skin Regeneration
With renewed energy, your skin can better support its natural repair and renewal cycles. Your complexion appears more refreshed, balanced, and restored.

3. Strengthen Skin Structure
5-ALA supports the formation of collagen and elastin, helping your skin maintain firmness - the foundation of smooth, supple skin texture.

4. Preserve Skin Hydration
Over time, the skin barrier becomes more delicate. By supporting healthy cellular metabolism, 5-ALA helps strengthen the barrier so your skin can retain moisture more effectively. The result: a nourished, protected, comfortably hydrated skin feel.

The Results Our Community Loves

Preventive Skincare

Looking for skincare that works early and supports your skin in the long run?

We believe in preventive skincare powered by 5-ALA.

5-ALA supports cellular activity and keeps your skin’s natural renewal processes moving - for smoother, clearer-looking skin today and the confidence of knowing your complexion will stay radiant tomorrow.

Skin in Balance

Does your skin tend to flush easily or look stressed?

A slowed-down renewal process is often the reason.

Our active ingredient 5-ALA supports natural regeneration and reinforces the skin’s protective functions. As a result, redness fades, irritation calms, and your complexion looks noticeably more even.

Deep Hydration

Dry, tight skin even though you’re using rich moisturizers?

Moisture alone isn’t always enough - your skin needs support to hold on to it. Clinical studies show that 5-ALA sustainably improves the skin’s moisture levels.

The result: skin that looks plump, fresh, and deeply hydrated.

Natural Glow Booster

Dull, tired-looking skin - even with a dedicated routine?

In many cases, the skin is simply lacking energy. Our active ingredient 5-ALA supports mitochondrial processes essential for cellular energy production - helping your skin regain its radiance quickly and naturally.

Refined Skin Texture

Uneven texture or enlarged pores?

This is often linked to a slowed cellular renewal process.

5-ALA supports the natural renewal cycle and helps rebalance overall skin texture - for visibly refined pores, smoother contours, and a more even-looking complexion.

Ingredients

These Ingredients Make the Difference

Japanese Herbal Extracts

A blend of traditional Japanese plant extracts such as angelica, turmeric, lithospermum, and phellodendron. They provide antioxidant benefits, soothe the skin, and support regeneration.

Ideal for: soothing, protection, regeneration

Shea Butter

Extracted from the nuts of the African shea tree, rich in vitamins and essential fatty acids. Deeply nourishes, protects against moisture loss, and leaves the skin soft and supple.

Ideal for: nourishing care, protection, softness

Resveratrol

A powerful plant-derived antioxidant from Japanese knotweed. Protects the skin from environmental stressors, helps prevent premature aging, and supports natural renewal.

Ideal for: protection, renewal, radiance

Step 1

Step 2

Step 3

FAQs

What is 5-ALA in skincare?

5-ALA (5-Aminolevulinic Acid) is a naturally occurring amino acid that supports cellular energy production.

Found in small amounts in foods like spinach and tomatoes, 5-ALA helps energize skin cells, making it a powerful ingredient for improving hydration, firmness, and glow.

How does 5-ALA work on the skin?

5-ALA stimulates the mitochondria, known as the "powerhouses" of cells.

This boosts the production of ATP (cellular energy), which helps the skin to generate collagen and elastin, retain moisture, and regenerate more effectively - resulting in smoother, more radiant skin.

Is 5-ALA safe for daily use?

All our 5-ALA skincare products are dermatologically tested and suitable for daily use as part of your skincare routine.

When can I expect to see visible results with 5-ALA skincare?

In a clinical study, participants saw a measurable increase in skin hydration after just 4 weeks, along with a visible reduction in wrinkle depth and fine lines. Results may vary depending on skin type and consistency of use.

Is 5-ALA a natural skincare ingredient?

Yes. 5-ALA occurs naturally in the human body and in small amounts in foods like spinach, tomatoes, and potatoes.

In skincare, it is biotechnologically derived for purity, safety, and effectiveness.

Can I combine 5-ALA with other skincare ingredients?

Absolutely. 5-ALA pairs well with hydrating agents like hyaluronic acid, barrier-supporting ingredients like ceramides, and even brightening actives like Vitamin C. It’s a versatile and gentle base for many routines.

Is there scientific research supporting the effectiveness of 5-ALA in skincare?

Yes. A Japanese double-blind clinical study confirmed that 5-ALA significantly increased skin moisture and reduced the depth of wrinkles after just four weeks of regular use.

Source: Naraoka et al., Health Journal, 2020.

Is 5-ALA vegan and cruelty-free?

Yes. The 5-ALA used in KIYOMI SKIN products is vegan, biotechnologically produced, and our skincare is never tested on animals.

What are the skincare benefits of 5-ALA?

5-ALA is ideal for anyone looking to:

Deep hydration and moisture retention
Visible reduction in fine lines and wrinkles
Improved skin elasticity and firmness
Supports cell renewal and repair
Long-term radiance and skin resilience

Is 5-ALA safe for all skin types?

Yes. 5-ALA is dermatologically tested and considered safe for all skin types, including sensitive skin.

At KIYOMI SKIN, we formulate with clean, biocompatible ingredients to ensure high tolerance and daily use.

Who should use 5-ALA skincare products?

5-ALA is perfect for those looking to:

Improve skin hydration and glow
Prevent or reduce signs of aging
Boost collagen production naturally
Strengthen and support skin from the inside out
Build a science-based, minimalist skincare routine.

Your Feedback

Kiyomi Community

@learn_withxavier

finally, I got that healthy glow we all love!

@niahlater

Glow = locked in.

@elizabethakelsey

Since I’m now 42, taking care of my skin is a priority for me. I love using natural products, fragrance-free products and I’m currently trying out the intensive night cream, which is super hydrating!

Reviews

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Skin longevity

Bakuchiol Serum

(5.0)

$49.90

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Cleansing Gel

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Travel Size Cleansing Oil

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Night & Day Intense Duo

Perfect All-Around Care: Intensive Day and Night Cream for Radiance and Regeneration

Day Cream with Double Amount of 5-ALA and Japanese Herbs for Smooth, Radiant Skin

Night Cream with 5-ALA and Resveratrol for Intensive Regeneration and Recovery

Give Your Skin the Care It Deserves