Step 2: Serum
Niacinamide + 5-ALA Serum
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Loved by our customers
Who is this product ideal for?
Made for skin that's dealing with visible pores, uneven texture, or a complexion that looks dull no matter what you try. If you want visibly smoother, more even skin - without a complicated routine - this is your serum.
Description
The Serum That Works Where Others Stop - Meet 5-ALA
Most serums work on the surface. The Kiyomi Skin Niacinamide Serum works deeper. 5-ALA — the cellular energy ingredient studied in Japanese dermatology for over two decades — activates your skin's natural renewal process. Paired with 5% Niacinamide and Hydrolyzed Hyaluronic Acid, the result is visibly refined pores, a more even complexion, and hydration that actually holds.
Why Niacinamide Works — And Why 5% Is The Right Dose
Niacinamide, also known as Vitamin B3, is one of the most research-backed active ingredients in modern skincare. It works on multiple levels simultaneously: it visibly refines pore appearance, evens skin tone, reduces redness, regulates sebum production, and strengthens the skin's moisture barrier — all without irritating even sensitive skin.
The question most often asked: why 5%, when other brands use 10%?
The answer is in the science. In a landmark double-blind, placebo-controlled split-face clinical study published in Dermatologic Surgery (Bissett et al., 2005), 50 subjects applied 5% niacinamide twice daily for 12 weeks. The results showed significant, measurable improvements across fine lines, skin texture, hyperpigmented spots, red blotchiness, and skin elasticity - all at the 5% concentration. A second peer-reviewed study by the same research group (International Journal of Cosmetic Science, 2004) confirmed the findings across a broader range of skin aging markers.
Higher concentrations do not equal stronger results. Formulations above 5–7% have been associated with increased rates of flushing and irritation in daily use — particularly in combination serums — without delivering measurably superior outcomes for pore refinement or skin tone. 5% niacinamide is the clinically validated sweet spot: effective enough to produce visible change, gentle enough for twice-daily use on all skin types.
In the Kiyomi Skin Niacinamide Serum, 5% niacinamide works in synergy with 5-ALA to amplify these results: where niacinamide refines and evens at the surface level, 5-ALA supports the cellular renewal process underneath — so the two ingredients compound each other's effect over time.
5-ALA: The Ingredient That Changes How Your Skin Behaves
Most skincare works from the outside in. 5-ALA works differently. As a precursor to cellular energy production, it supports your cell's mitochondrial activity, boosting natural cell renewal, collagen synthesis, and moisture retention. The result isn't just surface hydration. It's skin that progressively performs better.
Daily Use, Compounding Results
Unlike one-dimensional serums, the Niacinamide Serum is designed to deliver cumulative benefits:
Join thousands of customers who've made this their daily essential.
Dermatologically tested. Cruelty-free.
Sources: Bissett DL et al., "Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance," Dermatologic Surgery, 2005; Bissett DL et al., "Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin," International Journal of Cosmetic Science, 2004.
Füllmenge: 1 fl.oz. / 30ml
Packaged in Italian Glass
No Parabens or Silicones
Cruelty-free
No Perfume
GMO-free
No Microplastics

How 5-ALA supports your skin’s natural functions
The Results Our Community Loves
Natural Glow Booster
Skin in Balance
Refined Skin Texture
Deep Hydration
Preventive Skincare
These Ingredients Make the Difference
Niacinamide
Hydrolyzed Hyaluronic Acid
Buddleja Officinalis Flower Extract
Step 1 -
Apply
Step 2 -
Work In
Step 3 -
Let It Absorb



5-ALA (5-Aminolevulinic Acid) is a naturally occurring amino acid that supports cellular energy production.
Found in small amounts in foods like spinach and tomatoes, 5-ALA helps energize skin cells, making it a powerful ingredient for improving hydration, firmness, and glow.
5-ALA stimulates the mitochondria, known as the "powerhouses" of cells.
This boosts the production of ATP (cellular energy), which helps the skin to generate collagen and elastin, retain moisture, and regenerate more effectively - resulting in smoother, more radiant skin.
All our 5-ALA skincare products are dermatologically tested and suitable for daily use as part of your skincare routine.
In a clinical study, participants saw a measurable increase in skin hydration after just 4 weeks, along with a visible reduction in wrinkle depth and fine lines. Results may vary depending on skin type and consistency of use.
Yes. 5-ALA occurs naturally in the human body and in small amounts in foods like spinach, tomatoes, and potatoes.
In skincare, it is biotechnologically derived for purity, safety, and effectiveness.
Absolutely. 5-ALA pairs well with hydrating agents like hyaluronic acid, barrier-supporting ingredients like ceramides, and even brightening actives like Vitamin C. It’s a versatile and gentle base for many routines.
Yes. A Japanese double-blind clinical study confirmed that 5-ALA significantly increased skin moisture and reduced the depth of wrinkles after just four weeks of regular use.
Source: Naraoka et al., Health Journal, 2020.
Yes. The 5-ALA used in KIYOMI SKIN products is vegan, biotechnologically produced, and our skincare is never tested on animals.
5-ALA is ideal for anyone looking to:
- Deep hydration and moisture retention
- Visible reduction in fine lines and wrinkles
- Improved skin elasticity and firmness
- Supports cell renewal and repair
- Long-term radiance and skin resilience
Yes. 5-ALA is dermatologically tested and considered safe for all skin types, including sensitive skin.
At KIYOMI SKIN, we formulate with clean, biocompatible ingredients to ensure high tolerance and daily use.
5-ALA is perfect for those looking to:
- Improve skin hydration and glow
- Prevent or reduce signs of aging
- Boost collagen production naturally
- Strengthen and support skin from the inside out
- Build a science-based, minimalist skincare routine.
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