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Pore-refining Balancing

Step 2: Serum

Niacinamide + 5-ALA Serum

Sale price$49.90 USDIn stock

Tax excluded.

Visibly smaller pores, smoother texture - 5% Niacinamide refines skin texture & minimizes the appearance of enlarged pores. Measurable improvement in 4 weeks.

Your skin’s own energy, amplified - 5-ALA (Japan’s cellular energy ingredient) activates your skin’s natural renewal process. Faster cell turnover. Lasting radiance.

Hydration that stays - Hydrolyzed Hyaluronic Acid penetrates deeper than standard HA, locking in moisture at the cellular level for plump, bouncy skin all day.

Loved by our customers

As someone with very sensitive skin, I was initially skeptical, but this serum completely won me over. It absorbs quickly, and after just a few days, I noticed a visible improvement in my skin. - Nicole W.

Who is this product ideal for?

Made for skin that's dealing with visible pores, uneven texture, or a complexion that looks dull no matter what you try. If you want visibly smoother, more even skin - without a complicated routine - this is your serum.

Description

The Serum That Works Where Others Stop - Meet 5-ALA

Most serums work on the surface. The Kiyomi Skin Niacinamide Serum works deeper. 5-ALA — the cellular energy ingredient studied in Japanese dermatology for over two decades — activates your skin's natural renewal process. Paired with 5% Niacinamide and Hydrolyzed Hyaluronic Acid, the result is visibly refined pores, a more even complexion, and hydration that actually holds.

Why Niacinamide Works — And Why 5% Is The Right Dose

Niacinamide, also known as Vitamin B3, is one of the most research-backed active ingredients in modern skincare. It works on multiple levels simultaneously: it visibly refines pore appearance, evens skin tone, reduces redness, regulates sebum production, and strengthens the skin's moisture barrier — all without irritating even sensitive skin.

The question most often asked: why 5%, when other brands use 10%?

The answer is in the science. In a landmark double-blind, placebo-controlled split-face clinical study published in Dermatologic Surgery (Bissett et al., 2005), 50 subjects applied 5% niacinamide twice daily for 12 weeks. The results showed significant, measurable improvements across fine lines, skin texture, hyperpigmented spots, red blotchiness, and skin elasticity - all at the 5% concentration. A second peer-reviewed study by the same research group (International Journal of Cosmetic Science, 2004) confirmed the findings across a broader range of skin aging markers.

Higher concentrations do not equal stronger results. Formulations above 5–7% have been associated with increased rates of flushing and irritation in daily use — particularly in combination serums — without delivering measurably superior outcomes for pore refinement or skin tone. 5% niacinamide is the clinically validated sweet spot: effective enough to produce visible change, gentle enough for twice-daily use on all skin types.

In the Kiyomi Skin Niacinamide Serum, 5% niacinamide works in synergy with 5-ALA to amplify these results: where niacinamide refines and evens at the surface level, 5-ALA supports the cellular renewal process underneath — so the two ingredients compound each other's effect over time.

5-ALA: The Ingredient That Changes How Your Skin Behaves

Most skincare works from the outside in. 5-ALA works differently. As a precursor to cellular energy production, it supports your cell's mitochondrial activity, boosting natural cell renewal, collagen synthesis, and moisture retention. The result isn't just surface hydration. It's skin that progressively performs better. 

Daily Use, Compounding Results

Unlike one-dimensional serums, the Niacinamide Serum is designed to deliver cumulative benefits:



Day 1: lighter, more hydrated skin.
Week 2–3: visibly reduced pore size and more even tone.
Week 4+: clinical studies on 5-ALA show measurable improvement in skin moisture and a reduction in fine lines. The longer you use it, the more your skin responds.

Join thousands of customers who've made this their daily essential.

Dermatologically tested. Cruelty-free. 

Sources: Bissett DL et al., "Niacinamide: A B Vitamin that Improves Aging Facial Skin Appearance," Dermatologic Surgery, 2005; Bissett DL et al., "Topical niacinamide reduces yellowing, wrinkling, red blotchiness, and hyperpigmented spots in aging facial skin," International Journal of Cosmetic Science, 2004.

Application

Apply the KIYOMI SKIN Niacinamide Serum as needed, both
in the morning and in the evening. Use the pipette to apply 2-3 drops of the serum to your face and gently massage it in circular motions from the center of your face outwards. Allow it to fully absorb. Follow with a moisturizer.

Ingredients

Water, Pentylene Glycol, Niacinamide, Citrus Aurantium Amara (Bitter Orange) Flower Water, Fructooligosaccharides, Beta Vulgaris (Beet) Root Extract, Hydrolyzed Hyaluronic Acid, Cellulose Gum, Sodium Lactate, Sodium PCA, Aminolevulinic Acid Phosphate, Lactic Acid, Sodium Citrate, Inulin, Xanthan Gum, Citric Acid, Diammonium Ferric Pentetate, Glycine, Inositol, Urea, Cellulose, Fructose, Glucose, Argania Spinosa Kernel Oil, Propanediol, Buddleja Officinalis Flower Extract

Füllmenge: 1 fl.oz. / 30ml

Sale price$49.90 USD

Packaged in Italian Glass

No Parabens or Silicones

Cruelty-free

No Perfume

GMO-free

No Microplastics

Where Science Meets Results

How 5-ALA supports your skin’s natural functions

1. Activate Cellular Energy
5-ALA supports your skin’s natural energy production — forming the foundation for a healthy, radiant complexion.

2. Boost Regeneration
With increased cellular energy, the skin can better support its natural renewal and repair processes.

3. Strengthen Skin Structure
5-ALA helps promote the formation of collagen and elastin — for improved firmness and smoother-looking skin.

4. Maintain Hydration
A healthy cellular metabolism reinforces the skin barrier, helping it retain moisture and stay protected from dryness.

The Results Our Community Loves

Natural Glow Booster

Dull, tired-looking skin - even with a dedicated routine?

In many cases, the skin is simply lacking energy. Our active ingredient 5-ALA supports mitochondrial processes essential for cellular energy production - helping your skin regain its radiance quickly and naturally.

Skin in Balance

Does your skin tend to flush easily or look stressed?

A slowed-down renewal process is often the reason.

Our active ingredient 5-ALA supports natural regeneration and reinforces the skin’s protective functions. As a result, redness fades, irritation calms, and your complexion looks noticeably more even.

Refined Skin Texture

Uneven texture or enlarged pores?

This is often linked to a slowed cellular renewal process.

5-ALA supports the natural renewal cycle and helps rebalance overall skin texture - for visibly refined pores, smoother contours, and a more even-looking complexion.

Deep Hydration

Dry, tight skin even though you’re using rich moisturizers?

Moisture alone isn’t always enough - your skin needs support to hold on to it. Clinical studies show that 5-ALA sustainably improves the skin’s moisture levels.

The result: skin that looks plump, fresh, and deeply hydrated.

Preventive Skincare

Looking for skincare that works early and supports your skin in the long run?

We believe in preventive skincare powered by 5-ALA.

5-ALA supports cellular activity and keeps your skin’s natural renewal processes moving - for smoother, clearer-looking skin today and the confidence of knowing your complexion will stay radiant tomorrow.

Ingredients

These Ingredients Make the Difference

Niacinamide

Vitamin B3: visibly refines skin texture, strengthens the barrier, reduces redness, and regulates excess oil for a more even complexion.

Ideal for: texture refinement, barrier support, radiance

Hydrolyzed Hyaluronic Acid

A smaller-molecule form of hyaluronic acid that penetrates deeper into the skin - delivering intensive, long-lasting hydration and helping maintain moisture levels.

Ideal for: hydration boost, smoother skin

Buddleja Officinalis Flower Extract

Derived from the blossoms of the Asian butterfly bush. Rich in antioxidants, it protects against photo-aging, soothes sensitive skin, and promotes a more even complexion.

Ideal for: protection, soothing, even tone

Step 1 -
Apply

Morning and evening, dispense 2–3 drops with the dropper onto clean skin.

Step 2 -
Work In

Gently smooth it in with your fingertips, moving from the center of the face outward.

Step 3 -
Let It Absorb

Allow it to sink in completely before applying your moisturizer.

FAQs

More questions? We're here to help!

Contact Us

What is 5-ALA in skincare?

5-ALA (5-Aminolevulinic Acid) is a naturally occurring amino acid that supports cellular energy production.

Found in small amounts in foods like spinach and tomatoes, 5-ALA helps energize skin cells, making it a powerful ingredient for improving hydration, firmness, and glow.

How does 5-ALA work on the skin?

5-ALA stimulates the mitochondria, known as the "powerhouses" of cells.

This boosts the production of ATP (cellular energy), which helps the skin to generate collagen and elastin, retain moisture, and regenerate more effectively - resulting in smoother, more radiant skin.

Is 5-ALA safe for daily use?

All our 5-ALA skincare products are dermatologically tested and suitable for daily use as part of your skincare routine.

When can I expect to see visible results with 5-ALA skincare?

In a clinical study, participants saw a measurable increase in skin hydration after just 4 weeks, along with a visible reduction in wrinkle depth and fine lines. Results may vary depending on skin type and consistency of use.

Is 5-ALA a natural skincare ingredient?

Yes. 5-ALA occurs naturally in the human body and in small amounts in foods like spinach, tomatoes, and potatoes.

In skincare, it is biotechnologically derived for purity, safety, and effectiveness.

Can I combine 5-ALA with other skincare ingredients?

Absolutely. 5-ALA pairs well with hydrating agents like hyaluronic acid, barrier-supporting ingredients like ceramides, and even brightening actives like Vitamin C. It’s a versatile and gentle base for many routines.

Is there scientific research supporting the effectiveness of 5-ALA in skincare?

Yes. A Japanese double-blind clinical study confirmed that 5-ALA significantly increased skin moisture and reduced the depth of wrinkles after just four weeks of regular use.

Source: Naraoka et al., Health Journal, 2020.

Is 5-ALA vegan and cruelty-free?

Yes. The 5-ALA used in KIYOMI SKIN products is vegan, biotechnologically produced, and our skincare is never tested on animals.

What are the skincare benefits of 5-ALA?

5-ALA is ideal for anyone looking to:

  • Deep hydration and moisture retention
  • Visible reduction in fine lines and wrinkles
  • Improved skin elasticity and firmness
  • Supports cell renewal and repair
  • Long-term radiance and skin resilience

Is 5-ALA safe for all skin types?

Yes. 5-ALA is dermatologically tested and considered safe for all skin types, including sensitive skin.

At KIYOMI SKIN, we formulate with clean, biocompatible ingredients to ensure high tolerance and daily use.

Who should use 5-ALA skincare products?

5-ALA is perfect for those looking to:

  • Improve skin hydration and glow
  • Prevent or reduce signs of aging
  • Boost collagen production naturally
  • Strengthen and support skin from the inside out
  • Build a science-based, minimalist skincare routine.
Your Feedback

Kiyomi Community

@belky_ferrey

It’s my first time trying something with 5-ALA and now I get why it’s a big deal in Japan.

@inkarbekova_gumi

This routine makes me feel confident and radiant, like I just stepped out of a spa. ✨

@antoninakuss

Just found a new favorite for my skincare routine 🌸

Reviews